Clinical OMICS

MAR-APR 2017

Healthcare magazine for research scientists, labs, pathologists, hospitals, cancer centers, physicians and biopharma companies providing news articles, expert interviews and videos about molecular diagnostics in precision medicine

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14 Clinical OMICs March/April 2017 In the Clinic First Databank, Translational Software to Integrate Pharmacogenomic Data into EHRs Blackfynn, CHOP Deepen Partnership for Data Integration and Analysis of Pediatric Brain Tumors Blackfynn and Children's Hospital of Phil- adelphia (CHOP) said that Blackfynn's Data Platform will be used by CHOP and the Children's Brain Tumor Tissue Con- sortium (CBTTC) to bring together com- plex, nonidentifiable patient data for collaboration and analysis, with the aim of speeding translational medicine for brain cancer in children. CHOP and Blackfynn first began work- ing together a year ago with a focus on pathology data. Under the newly expanded relationship, Blackfynn will provide CHOP and CBTTC access to its data platform to allow for research using nonidentifiable patient data, including pathology, imaging, genomics, EEG, clin- ical and other data. The hope is that by making such varied datasets available, CHOP and CBTTC researchers can iden- tify relevant patterns for treatment of disease. "We share their core belief that trans- formational discovery will only occur when experts can effectively use the vast amounts of disparate, complex data generated in research," said Amanda Christini, M.D., Blackfynn president. "Blackfynn's Data Platform will funda- mentally enable this goal." n First Databank (FDB), a company that provides drug and medical device knowledge to health professionals, and Translational Software, a clinical deci- sion support tools developer, recently launched a collaboration to bring phar- macogenomics drug knowledge to clinical workflows, including electronic health records (EHRs). The joint effort will combine FDB's medicine man- agement expertise along with Transla- tional Software's genomic content . "With Translational Software's [knowledge] base from over 80 labs, we see a battle-tested repository of interpretive knowledge for genomic findings to build on top of," said George Robinson, senior product man- ager at FDB . "FDB has a long history of tight integration with many of the players in hospital EHRs, ambulatory EHRs, pharmacy management sys- tems, and increasingly, population health solutions." Don Rule, the founder and CEO of Translational Software, said that in addition to the network of labs the company works with now, it could also work with organizations that want to conduct in-house testing . "I think one of the things that is unique to the solution that we're offer- ing is that it allows folks to integrate genetic results from a variety of dif- ferent sources," said Chuck Tuchinda, president of FDB . "This solution will really make genetic testing results, their interpretation, and their impact in medications available to a bulk of clinicians because it can leverage results from external labs, internal labs, from anywhere they may be." Tuchinda added that FDB plans to provide "highly actionable data" so that when a clinician is about to pre- scribe a relevant drug and there is a known genetic result for that patient, the system can automatically inform them of dose or drug adjustments that are required . "One of the big dif- ferentiators of our partnership is it's focusing on the research insights that will actually change the prescriber 's behavior," Tuchinda noted. "At this point, we're prepared to support early adopters of the con- tent," Robinson said. "What we're learning is that we really need to work closely with our vendor partners to deliver solutions that are going to meet their unique needs." Currently, FDB is working with EHR and health information system vendors Epic Sys- tems, MEDITECH, and athenahealth . —Diana Kwon Steve Debenport / Getty Images pe-art / Getty Images

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