Clinical OMICS

SEP-OCT 2018

Healthcare magazine for research scientists, labs, pathologists, hospitals, cancer centers, physicians and biopharma companies providing news articles, expert interviews and videos about molecular diagnostics in precision medicine

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VOL. 5, Issue No. 5 September/October 2018 September/October 2018 Clinical OMICs 1 @ClinicalOMICs 30 | Keeping the Beat: Researchers Find New Genetic Variants Linked to Atrial Fibrillation, Suggesting New Treatment Targets 34 | U.K. Team Reports CRISPR–Induced Gene Rearrangements: New Findings Call the Precision of CRISPR- Cas9 Gene Editing into Question 37 | Exosomes Containing PD-L1 Could Predict Immunotherapy Responses: Immune-Evasion Mechanism May Help Explain the Differences in Responses to Immunotherapy 39 | NEW PRODUCTS 48 | INDUSTRY EVENTS New Tack for Neurodegenerative Disease Research Armed with new tools and lower cost sequencing, researchers take an omics approach to neurodegenerative diseases 12 The 100,000 Genomes Club Ten countries have announced plans and secured funding to sequence at least 100,000 genomes 40 3 | FROM THE EDITOR Clinical OMICs Evolves and Grows 8 | Patient Investment: GSK, 23andMe Forge Alliance to Develop Drugs via Genetics 16 | Smooth Sailing, So Far: Venter Institute Wins Early Skirmish in Lawsuit Filed by Human Longevity 20 | FEATURE Personalized Healthcare on the Go: Incorporating Consumer Devices and Disease-Specific Monitoring, Wearables are Changing Healthcare 26 | FEATURE Keeping up with the Genomes: Clinical Decision Support Tools Play Increasing Role in Precision Medicine Cover: Mon Oo Yee; Above (top right) wildpixel / Getty Images; (top left); (middle right) Wavebreakmedia Ltd / Getty Images; (bottom left) Natali_Mis / Getty Images; (bottom right) The labs of Wei Guo, Ph.D., and Xiaowei Xu, M.D., Ph.D., University of Pennsylvania

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