Clinical OMICS

MAR-APR 2018

Healthcare magazine for research scientists, labs, pathologists, hospitals, cancer centers, physicians and biopharma companies providing news articles, expert interviews and videos about molecular diagnostics in precision medicine

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VOL. 5, Issue No. 2 March/April 2018 March/April 2018 Clinical OMICs 1 @ClinicalOMICs 30| DATA & INFORMATICS Disruptive Research: Regeneron, Five Biopharmas Commit $50M to Exome Sequencing of all 500,000 U.K. Biobank Samples by 2019 34 | IN THE LAB The Genetics of ASD: Cold Spring Harbor Autism Study Sheds New Light on Children with De Novo Mutations 39 | NEW PRODUCTS 40 | FEATURE The Human Genome at 15: Researchers Who Were There Discuss the Human Genome Project 44 | PRECISION MEDICINE As Maine Goes…: MCGI Tests Innovative Statewide Genomic Cancer Treatment Model 48 | INDUSTRY EVENTS Beyond Short Reads Up-and-Coming Genomics Technologies Reveal Previously Unseen Structural Variants 20 Genomics gets Personal Despite Data and Privacy Challenges, Decreasing Cost Ushers in the Age of Personalized Whole- Genome Sequencing 26 3 | NEWS Seqster Platform to Integrate Genomic, EHR, and Wearable Health Data 10 | FROM THE EDITOR Mitigating Cancer Care Disparities 11 | OP-ED Real-World Evidence in the Era of Advanced Diagnostics 12 | FEATURE New Kids on the Blockchain: Luna DNA Hopes It Has the Winning Model for Blockchain Genomics 16 | DIAGNOSTICS Standing Sentinel: A Multi-Analyte Test Marks a New Milestone in Early Cancer Detection Cover: The Jackson Laboratory; Above (top right): Andrew Brookes / Getty Images; (top left) Ardy Arianpour/ Seqster; (middle left) chombosan / Getty Images; (middle right) Regeneron; (bottom left) Geisinger Health System.

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